Table 3 Top pathways for miR-132 and miR-210 predicted mRNA targets across all time points

Molecular Mechanisms of Cancer

<0.0001

0.0301

E2F5, CFLAR, ADCY3, ARHGEF10, CDKN1A, MAPK1, TGFB2, PRKD1, RAP2B, PRKAG2, FOXO1

RAR Activation

0.0001

0.0398

ADCY3, MAPK1, TGFB2, PRKD1, PRKAG2, NCOR1, GTF2H1

VDR/RXR Activation

0.0001

0.0641

CDKN1A, TGFB2, PRKD1, NCOR1, FOXO1

Breast Cancer Regulation by Stathmin1

0.0001

0.0366

E2F5, ADCY3, ARHGEF10, CDKN1A, MAPK1, PRKD1, PRKAG2

ErbB Signaling

0.0001

0.0581

HBEGF, MAPK1, PRKD1, NRG2, FOXO1

Pancreatic Adenocarcinoma Signaling

0.0003

0.0472

E2F5, HBEGF, CDKN1A, MAPK1, TGFB2

Cell Cycle: G1/S Checkpoint Regulation

0.0005

0.0625

E2F5, CDKN1A, TGFB2, FOXO1

PPARα/RXRα Activation

0.0005

0.0335

ADCY3, MAPK1, TGFB2, CAND1, PRKAG2, NCOR1

Leptin Signaling

0.0008

0.0541

ADCY3, MAPK1, PRKAG2, FOXO1

Acute Myeloid Leukemia Signaling

0.0009

0.0519

KITLG, MAPK1, TCF7L2, TCF7L1

Phospholipase C Signaling

0.0022

0.0126

ADCY5, BTK, PPP1CB

Dopamine Receptor Signaling

0.0033

0.0256

ADCY5, PPP1CB

CDK5 Signaling

0.0052

0.0202

ADCY5, PPP1CB

NAD Biosynthesis III

0.0066

0.1670

NMNAT2

Phosphatidylcholine Biosynthesis I

0.0078

0.1430

PCYT1B

NAD Salvage Pathway III

0.0078

0.1430

NMNAT2

Cellular Effects of Sildenafil (Viagra)

0.0089

0.0155

ADCY5, PPP1CB

β-adrenergic Signaling

0.0093

0.0150

ADCY5, PPP1CB

Calcium Transport I

0.0100

0.1110

ATP2B3

Dopamine-DARPP32 Feedback in cAMP Signaling

0.0135

0.0124

ADCY5, PPP1CB