Fig. 4

NRXN3 isoform representation across brain region. NRXN3 was found to be a gene with extreme differences in isoform representation. The top panel shows 5 isoforms annotated by RefSeq and the middle panel focuses on the difference between the major isoforms (Dup0 and Dup5). The bottom panel shows the representation of all isoforms as a fraction of the whole gene expression, combining Dup1 and Dup2 into “minor isoforms”. Dup0 is the major isoform in all Broadmann’s areas, insula, amygdala, and hippocampus. Dup5 is the major isoform in cerebellum and raphae nuclei. Samples from the posterior putamen are mixed