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Table 2 Positions of QTLs associated with trabecular traits

From: Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture

QTL Trait Chr logP 99th % threshold logP Sig H2 r logP H2 r 50 % CI 90 % CI 95 % CI
         Simulation Li (2011)   
         Position Width (Mb) Position Width (Mb) Position Width (Mb) Position Width (Mb)
Trl1 BV/TV 2.00 6.67 5.01 0.01 0.60 2.46 130.48-130.68 0.20 129.9-130.5 0.60 128.08-132.8 4.70 126.2-135.6 9.40
Trl2 BV/TV 2.00 6.31 5.01 0.01 0.67 3.37 121.9-122.2 0.30 119.6-123.4 3.80 121.7-122.4 0.70 115.6-124.9 9.30
Trl3 Tb.N 8.00 5.63 4.88 0.01 0.61 2.42 37.2-40.47 3.27 37.8-41.2 3.40 31.8-43.9 12.40 30.8-46.9 16.10
Trl4 Tb.Th 7.00 7.87 5.14 0.01 0.86 6.75 64.6-64.8 0.20 63.7-65.6 1.90 63.8-65.7 1.90 62.7-68.1 5.40
Trl5 Tb.Th 7.00 5.36 5.14 0.01 0.73 12.77 73.4-73.5 0.13 73.2-73.7 0.52 70.4-75.1 4.74 66.01-77.9 10.73
Trl6 Conn.D 14.00 6.36 5.17 0.01 0.66 12.77 69.8-79.74 9.94 70.7-79.2 8.50 66.7-77.2 10.62 64.7-77.1 13.50
  1. Chr chromosome; logP = negative 10-base logarithm of P value; Sig = genome-wide significance level; 99th % threshold logP = threshold used to define cut-off for QTL peaks (Fig. 4); Hr 2 = regional heritability. Positions and widths of the simulation-based 50, 90, and 95 % CIs are given, as well as 50 % CIs calculated after Li (2011). (See text.)