Fig. 2

PKSs and NRPSs in algae. a Examples of type I PKSs and NRPSs predicted from algal genome sequences. Note that in Chlorella variabilis, separate genes are annotated for the N-terminal Lig and KS domains (identifiers 7741 and 22890, respectively), but we assumed that they are part of the large type I PKS gene (57723). EsiPKS1 may be truncated as both ends of the EsiPKS1 gene are close to the ends of the contig. b Section of scaffold 46 of the Aureococcus anophagefferens genome (position 73,000 - 145,000). Shown are gene models according to the gene prediction in v.1 of the genome together with the corresponding protein identifiers. Wide bars depict exons, narrow bars depict introns. Also shown are sites that encode the conserved GxDSL motif of ACP domains, which we found 15 times in forward direction, but not in reverse direction. Domain abbreviations: KS, ketosynthase; AT, acyltransferase; DH, dehydratase; ER, enoylreductase; KR, ketoreductase; ACP, acyl carrier protein; MT, methyltransferase; Lig, AMP-dependent synthetase/ligase; TE, thioesterase; C, condensation domain; A, adenylation domain; PCP, peptidyl carrier protein; Red, reducing domain