| | | WT |
|---|
| | | Up | NC | Down | Total |
|---|
| | Up | 45 (13↓,31↑) | 12(3↓,8↑) | 16(6↓,9↑) | 73(22↓,48↑) |
YAC128 | NC | 10(7↓,2↑) | 8(5↓,3↑) | 7(4↓,3↑) | 25(16↓,8↑) |
| | Down | 17(10↓,2↑) | 9(8↓,1↑) | 22(21↓,1↑) | 48(39↓,4↑) |
| | Total | 72 | 29 | 45 | 146 |
- Numbers of genes significant for each TANOVA pattern of change over time, given as number (number of genes down-regulated in YAC128↓,number of genes up-regulated in YAC128↑): some genes showed a mixed pattern of change and have not been included. NC = no change. For instance in the top left hand corner, 45 genes were seen to increase in expression with age in YAC128 and wild-type striata, and of those 13 were reduced in expression in WT compared with YAC128 expression and 31 were increased in expression compared with YAC128 expression.
