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Fig. 3 | BMC Genomics

Fig. 3

From: Reconstruction of temporal activity of microRNAs from gene expression data in breast cancer cell line

Fig. 3

Synergistic network of miRNAs: (a) Schematic of miRNA-miRNA synergistic network construction. b Predicted synergistic interaction pairs of miRNAs in the form of network in breast cancer. Here cyan squares represent breast cancer associated miRNAs in previous studies and red squares represent new miRNAs with no previous involvement in breast cancer studies. c Degree distribution. Right panel: scatter plot of the node degree (number of connections to a specific miRNA) vs. the number of nodes (miRNAs) revealed the power law degree distribution. Left panel: Distribution of miRNA as a function of their node number. We found several hub miRNAs with large number of connections

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