Table 1 The top 20 miRNAs with highest degree in breast cancer integrated regulatory network. The degree of a node is the sum of in-coming and out-going connections with other nodes in the network. PMIDs denote the ‘pubmed’ identification numbers
Rank | miR Name | Degree | Breast cancer related | PMIDs |
|---|---|---|---|---|
1 | hsa-miR-335-5p | 220 | Yes | 18185580 |
2 | hsa-miR-124-3p | 185 | Yes | 22333974, 22085528 |
3 | hsa-miR-26b-5p | 174 | Yes | 23374284, 21510944 |
4 | hsa-miR-16-5p | 137 | Yes | 22583478 |
5 | hsa-let-7b-5p | 114 | Yes | 23339187 |
6 | hsa-miR-615-3p | 110 | No | -- |
7 | hsa-miR-155-5p | 107 | Yes | 23372341, 16103053 |
8 | hsa-miR-92a-3p | 105 | Yes | 23052693 |
9 | hsa-miR-1 | 96 | No | -- |
10 | hsa-miR-21-5p | 90 | Yes | 23052693, 19419954 |
11 | hsa-miR-484 | 88 | No | -- |
12 | hsa-miR-30a-5p | 86 | Yes | 22476851, 23389917 |
13 | hsa-miR-193b-3p | 82 | Yes | 19701247 |
14 | hsa-miR-34a-5p | 79 | Yes | 23032974 |
15 | hsa-miR-17-5p | 78 | Yes | 16940181, 20505989 |
16 | hsa-miR-192-5p | 77 | No | -- |
17 | hsa-miR-324-5p | 73 | No | -- |
18 | hsa-miR-98-5p | 72 | Yes | 18812439 |
19 | hsa-miR-324-3p | 71 | No | -- |
20 | hsa-miR-125b-5p | 64 | Yes | 22693547, 21444677 |