Table 2 The top 20 TFs or TGs with highest degree in breast cancer integrated regulatory network. The degree of a node is the sum of in-coming and out-going connections with other nodes in the network. PMIDs denote the ‘pubmed’ identification numbers
Rank | TF Name | Degree | Breast cancer related | PMIDs |
|---|---|---|---|---|
1 | SP1 | 371 | Yes | 19812674 |
2 | TCF12 | 343 | Yes | 20525248 |
3 | SP4 | 337 | No | -- |
4 | SP3 | 309 | No | -- |
5 | SP2 | 259 | Yes | Breast cancer database (www.breastcancerdatabase.org) |
6 | MYOD1 | 222 | Yes | 20525248 |
7 | JUN | 215 | Yes | 20525248 |
8 | ERG | 211 | No | -- |
9 | MYF6 | 199 | No | -- |
10 | ETV7 | 189 | Yes | 20525248 |
11 | ARID5B | 187 | No | -- |
12 | MYF5 | 183 | No | -- |
13 | EGR2 | 182 | Yes | 20525248 |
14 | MYOG | 182 | No | -- |
15 | ETS1 | 181 | Yes | 20668451, 20525248 |
16 | ASCL1 | 180 | No | -- |
17 | MYC | 178 | Yes | 20525248 |
18 | ETS2 | 176 | Yes | Breast cancer database (www.breastcancerdatabase.org) |
19 | TCF3 | 174 | No | -- |
20 | ELF2 | 173 | No | -- |