Table 2 Up-regulated proteins involved in stress response and osmoregulation in Red Sea newly released nauplii larvae of B.amphitrite

Stress response/defense/energy

AAN74984.1

348386_5

70 kDa heat shock protein 70 kDa (HSP70)

3

28

2.07

0.078

XP_001951792.1

284615_1

heat shock 70 kDa protein 4 L ((HSP70-4 L)

2

31

2.78

0.043

XP_969171.1

221326_2

chaperonin (CPN)

1

34

1.71

0.283

AER95784.1

112034_2 (+1)

chaperonin containing TCP1subunit 4(CPN-TCP1-4)

2

30

1.6

0.07

BAG72108.1

333804_5

chaperonin eta subunit (CPN-eta)

3

29

1.6

0.028

XP_004206182.1

216349_6 (+2)

major egg antigen (MGN)

8

28

2.31

0.057

XP_001606473.2

235958_8

T-complex protein 1 subunit zeta- isoform 1 (TCP1)

2

20

2

0.043

BAA92814.1

379389_7

annexin IX-A (AnxIXA)

2

30

3

0.043

BAG41813.1

149743_6

cyclophilin A (CyPA)

4

44

2.21

0.088

XP_001521816.2

331314_1 (+2)

collagen alpha-3(IV) chain (Col4)

1

13

2.7

0.068

ABZ91537.1

11340_21

vitellogenin (VTG)

3

9

5.53

0.821

XP_002741413.1

9957_2

vitellogenin structural gene-1 (VTG1)

3

12

1.96

0.076

Osmoregulation

AEX07319.1

136693_6

Na+/K + −ATPase alpha subunit (H + K + αATPase)

6

21

1.85

0.168

AAA35578

356633_2

ATPase

2

50

2.03

0.017

XP_003817086.1

110200_6

sodium-dependent phosphate transport protein 2C(SLC2C)

3

60

4.35

0.2

XP_003244453.1

333233_4

v-type proton ATPase 116 kDa subunit a isoform 1(ATP6V0A1)

2

12

2.91

0.432

P31401.1

358029_1

v-type proton ATPase subunit B (ATPV0B)

2

64

3.05

0.367

ADI56517.1

263296_2

voltage-dependent anion channel 2 (VDAC2).

2

62

1.75

0.017

XP_004073305.1

259151_2

neuronal acetylcholine receptor subunit non-alpha-3 (α7-nAChR)

1

17

4.09

0.076

ADO27772.1

30169_8 (+1)

carbonic anhydrase (CA)

1

5

4

0.13

AFS60116.1

324487_3

selenoprotein M (SelM)

1

28

4.4

0.119

Muscle contraction

EFX86510.1

142581_8

myosin essential light chain (MLC)

1

16

2.65

0.249

XP_002425291.1

233725_2

paramyosin(PM)

1

9

2.71

0.057

XP_002432355.1

385389_2 (+1)

paramyosin, long form (PM-L)

1

32

1.9

0.139

EGI57423.1

295447_2

titin(TTN)

1

8

2.91

0.07

AAT77811.1

33648_2 (+1)

calpain B(CalpB)

1

35

1.84

0.035

Development/morphogenesis

ADV40137.1

350939_3

actin 5C (ACT5C)

2

60

3.6

0.07

XP_003696514.1

286277_1

actin, indirect flight muscle-like isoform 2(ACTIFM2)

2

96

2.29

0.135

XP_003696514.1

103842_3

actin, indirect flight muscle-like isoform 2 (ACTIFM2)

3

62

2.17

0.043

ACO11823.1

368856_3

actin, muscle (ACTM)

3

26

1.72

0.143

NP_001029376.1

358955_6

tubulin alpha-1C chain (TUBA1C)

2

15

3.01

0.204

XP_003220514.1

322186_3

tubulin alpha-1C chain (TUBA1C)

2

67

1.63

0.064

XP_001928233.1

258099_4 (+1)

tubulin alpha-1D chain (TUBA1D)

1

22

4.17

0

XP_624843.2

161549_1 (+1)

filamin-B (FLNB)

2

26

2.31

0.028

Cellular metabolism

ACX53990.1

291866_1 (+3)

ubiquinol-cytochrome c reductase complex (UQCCR)

1

13

1.83

0.057

EEZ99338.1

333062_1

cytochrome P450 6BQ13 (CY-P450 6BQ13)

1

8

4.13

0.224

XP_970215.1

359961_2

cytochrome P450 CYP6BK17 (CY-P450 6BQ13)

1

2

3.15

0.028

XP_004079962.1

302118_1 (+1)

dehydrogenase/reductase SDR family member 4(DHRS4)

2

44

3.21

0.132

ZP_09403919.1

328617_1

short chain oxidoreductase (SCOR)

2

25

2.14

0.043

XP_003204363.1

272396_1

reticulon-4-interacting protein 1, mitochondrial (RTN4IP1)

1

26

3.64

0.081

ZP_01905843.1

388126_2

oxidoreductase, short chain dehydrogenase/reductase family protein(SDR)

1

13

2.38

0.078

XP_003701373.1

142763_2

trans-1,2-dihydrobenzene-1,2-diol dehydrogenase(DHDH)

1

7

1.83

0.028

Signaling pathways

XP_966512.1

40595_3

GTP-binding nuclear protein Ran isoform 1 (RanGTPBP1)

6

37

1.93

0.067

XP_002432661.1

92938_6

GTP-binding protein SAR1B (GTP-BP-SAR1b)

1

75

4.8

0.247

XP_001945117.1

198588_2

guanine nucleotide-binding protein G(i) subunit alpha(GNBPα)

1

6

1.93

0.067

NP_001040272.1

194501_4

receptor for activated protein kinase C isoform 2 (RACK2)

3

41

1.63

0.092

NP_001037203.1

238662_1 (+1)

innexin 2 (INX2)

3

23

1.96

0.073

XP_003488474.1

362217_1

epidermal growth factor receptor substrate 15 (EGFR15)

1

19

2

0.159