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Fig. 1 | BMC Genomics

Fig. 1

From: Epigenetic modification with trichostatin A does not correct specific errors of somatic cell nuclear transfer at the transcriptomic level; highlighting the non-random nature of oocyte-mediated reprogramming errors

Fig. 1

Microarray graphical results. a Overview of differential gene expression in CTR-NT and TSA-NT day 7 blastocysts compared to IVF counterparts. The total number of differentially regulated genes which comprised the total number of upregulated and downregulated genes is shown by directions of arrows. The Venn diagram shows the overlap between deregulated genes in both SCNT groups. b Venn diagram illustration of the overlap between genes predominantly and exclusively expressed in CTR-NT, TSA-NT and IVF -derived blastocysts. c Two-dimensional principal component analysis (PCA) indicating the source of variation in the overall transcriptional profiles of CTR-NT vs. IVF and TSA-NT vs. IVF in this study with the transcriptional profile of in vivo blastocysts obtained from the study of Gad et al. (2012) using the same array platform

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BMC Genomics

ISSN: 1471-2164

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