Table 2 Performance of Dintor gene prioritization tool compared to results reported in [40]
From: Dintor: functional annotation of genomic and proteomic data
Tool namea | Response rate | TPR in top 5 % | TPR in top 10 % | TPR in top 30 % | Median |
|---|---|---|---|---|---|
Candid [51] | 100 % | 21.4 % | 33.3 % | 64.3 % | 18.11 |
Dintor | 100 % | 31.0 % | 42.9 % | 59.5 % | 23.62 |
Endeavour-CS [52] | 100 % | 26.2 % | 42.9 % | 90.5 % | 11.16 |
Endeavour-GW [52] | 100 % | 28.6 % | 38.1 % | 71.4 % | 15.49 |
GeneDistiller [53] | 97.6 % | 26.2 % | 47.6 % | 78.6 % | 11.11 |
GeneWanderer-DK [54] | 88.1 % | 11.9 % | 21.4 % | 52.4 % | 22.97 |
GeneWanderer-RW [54] | 95.2 % | 16.7 % | 26.2 % | 61.9 % | 22.11 |
Pinta-CS [55] | 100 % | 28.6 % | 31.0 % | 71.4 % | 18.87 |
Pinta-GW [55] | 100 % | 26.2 % | 31.0 % | 71.4 % | 19.03 |
ToppGene [16] | 97.6 % | 35.7 % | 42.9 % | 52.4 % | 16.80 |