Fig. 2

cChIP-seq for H3K4me3 on 10,000 cells in K562 cells. a Pearson’s correlation values heatmap for replicates of cChIP-seq on 10,000 cells and ENCODE data. b UCSC genome browser snapshot showing H3K4me3 signal (RPKM input normalized) for the three datasets at the hemoglobin locus (chr11). c Venn diagram showing the number of unique and common regions enriched for H3K4me3 across cChIP-seq, Broad and SYDH datasets. d Heatmap representation of the signal intensity (RPKM input normalized) across the three datasets in a 5 kb window centered at all protein-coding transcription start sites (TSS) [GENCODE assembly GRCh37]. R1: replicate 1; R2: replicate 2