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Fig. 1 | BMC Genomics

Fig. 1

From: Power estimation and sample size determination for replication studies of genome-wide association studies

Fig. 1

When log-odds ratio is normally distributed, the power of replication study possesses non-normality. Assume the effect size follows normal distribution N(0.15,0.052). The standard error of log-odds ratio is σ (2)=0.05 in the replication study. The significance level of the replication study is α (2)=5×10−3. The histogram of the power in the replication study possesses non-normality

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BMC Genomics

ISSN: 1471-2164

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