From: Power estimation and sample size determination for replication studies of genome-wide association studies
Non-effect allele
Effect allele
Total
Control
\(n_{00}^{(j)}\)
\(n_{01}^{(j)}\)
\(2n_{0}^{(j)}\)
Case
\(n_{10}^{(j)}\)
\(n_{11}^{(j)}\)
\(2n_{1}^{(j)}\)
\(n_{00}^{(j)}+n_{10}^{(j)}\)
\(n_{01}^{(j)}+n_{11}^{(j)}\)
2n (j)