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Fig. 1 | BMC Genomics

Fig. 1

From: Chronic binge alcohol administration dysregulates global regulatory gene networks associated with skeletal muscle wasting in simian immunodeficiency virus-infected macaques

Fig. 1

Functional enrichment of CBA-altered mRNAs at end-stage SIV disease. a The enriched pathways analyzed by gene set enrichment analysis revealed significant association of genes of CBA/SIV group in fifteen main gene sets. b Three representative plots of enriched gene sets in the CBA/SIV group. Enrichment score (ES) is the degree to which a gene set is overrepresented at the top or bottom of a ranked list of genes. NES is normalized enrichment score. Nominal p-value (NOM p-val) estimates the statistical significance of the enrichment score for a single gene set. False discovery rate (FDR) is the estimated probability that a gene set with a given NES represents a false positive finding

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BMC Genomics

ISSN: 1471-2164

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