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Fig. 2 | BMC Genomics

Fig. 2

From: Chronic binge alcohol administration dysregulates global regulatory gene networks associated with skeletal muscle wasting in simian immunodeficiency virus-infected macaques

Fig. 2

Functional enrichment of CBA-altered miRNAs at end-stage SIV disease. a CBA-dependent differentially expressed miRNAs. b Pathways enriched by predicted target genes of differentially expressed miRNAs as determined by miRSystem. c qPCR confirmation of miRNAs and target genes: Relative miRNA expression of miR-34a, miR-10b and miR-20 in the skeletal muscle of control (white bars), SUC/SIV (grey bars), and CBA/SIV (black bars) macaques determined by qPCR. Relative mRNA expression of ESR1, BCL2, and KRAS in the skeletal muscle of control (white bars), SUC/SIV (grey bars), and CBA/SIV (black bars) macaques determined by qPCR. Values are mean ± SEM. *p < 0.05 vs. Control and SUC/SIV

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BMC Genomics

ISSN: 1471-2164

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