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Table 2 CBA-dependent alterations in promoter methylation at end-stage SIV infection

From: Chronic binge alcohol administration dysregulates global regulatory gene networks associated with skeletal muscle wasting in simian immunodeficiency virus-infected macaques

Biological process Count % P-Value Benjamini
Regulation of synaptic transmission 7 0.5 0.00027 0.3
Regulation of transmission of nerve impulse 7 0.5 0.00042 0.23
Regulation of neurological system process 7 0.5 0.00052 0.15
Regulation of system process 8 0.5 0.0043 0.6
Cellular process 81 5.6 0.0057 0.65
Regulation of biological quality 19 1.3 0.0068 0.67
Alcohol metabolic process 9 0.6 0.0073 0.65
Neurotransmitter metabolic process 3 0.2 0.0091 0.69
Vesicle-mediated transport 10 0.7 0.014 0.74
Cell communication 12 0.8 0.015 0.75
Transmembrane receptor protein tyrosine kinase signaling pathway 6 0.4 0.016 0.75
Cell-cell signaling 10 0.7 0.017 0.75
Glucose metabolic process 5 0.3 0.018 0.73
Regulation of neurogenesis 5 0.3 0.024 0.81
Establishment of localization in cell 12 0.8 0.024 0.79
Enzyme linked receptor protein signaling pathway 7 0.5 0.025 0.79
Negative regulation of biological process 20 1.4 0.026 0.78
Intracellular transport 10 0.7 0.029 0.8
Cellular component biogenesis 13 0.9 0.031 0.81
Negative regulation of programmed cell death 7 0.5 0.031 0.8
Regulation of cellular component organization 8 0.5 0.031 0.79
Regulation of phosphorylation 8 0.5 0.034 0.78
Cellular ion homeostasis 7 0.5 0.037 0.8
Regulation of phosphorus metabolic process 8 0.5 0.041 0.8
Cellular localization 12 0.8 0.041 0.79
Regulation of multicellular organismal process 12 0.8 0.044 0.8
RNA metabolic process 12 0.8 0.044 0.8
  1. Count: number of genes involved in the term; %: percentage of involved genes/total genes; P-Value: modified fisher exact P-value, EASE Score; Benjamini: adjusted P-value using Benjamini-Hochberg procedure