Table 2 CBA-dependent alterations in promoter methylation at end-stage SIV infection
Biological process | Count | % | P-Value | Benjamini |
|---|---|---|---|---|
Regulation of synaptic transmission | 7 | 0.5 | 0.00027 | 0.3 |
Regulation of transmission of nerve impulse | 7 | 0.5 | 0.00042 | 0.23 |
Regulation of neurological system process | 7 | 0.5 | 0.00052 | 0.15 |
Regulation of system process | 8 | 0.5 | 0.0043 | 0.6 |
Cellular process | 81 | 5.6 | 0.0057 | 0.65 |
Regulation of biological quality | 19 | 1.3 | 0.0068 | 0.67 |
Alcohol metabolic process | 9 | 0.6 | 0.0073 | 0.65 |
Neurotransmitter metabolic process | 3 | 0.2 | 0.0091 | 0.69 |
Vesicle-mediated transport | 10 | 0.7 | 0.014 | 0.74 |
Cell communication | 12 | 0.8 | 0.015 | 0.75 |
Transmembrane receptor protein tyrosine kinase signaling pathway | 6 | 0.4 | 0.016 | 0.75 |
Cell-cell signaling | 10 | 0.7 | 0.017 | 0.75 |
Glucose metabolic process | 5 | 0.3 | 0.018 | 0.73 |
Regulation of neurogenesis | 5 | 0.3 | 0.024 | 0.81 |
Establishment of localization in cell | 12 | 0.8 | 0.024 | 0.79 |
Enzyme linked receptor protein signaling pathway | 7 | 0.5 | 0.025 | 0.79 |
Negative regulation of biological process | 20 | 1.4 | 0.026 | 0.78 |
Intracellular transport | 10 | 0.7 | 0.029 | 0.8 |
Cellular component biogenesis | 13 | 0.9 | 0.031 | 0.81 |
Negative regulation of programmed cell death | 7 | 0.5 | 0.031 | 0.8 |
Regulation of cellular component organization | 8 | 0.5 | 0.031 | 0.79 |
Regulation of phosphorylation | 8 | 0.5 | 0.034 | 0.78 |
Cellular ion homeostasis | 7 | 0.5 | 0.037 | 0.8 |
Regulation of phosphorus metabolic process | 8 | 0.5 | 0.041 | 0.8 |
Cellular localization | 12 | 0.8 | 0.041 | 0.79 |
Regulation of multicellular organismal process | 12 | 0.8 | 0.044 | 0.8 |
RNA metabolic process | 12 | 0.8 | 0.044 | 0.8 |