Fig. 1

Growth parameters of Microbispora ATCC-PTA-5024 WT strain. Each value is the mean of three independent measurements performed on parallel cultivations. Error bars represent standard deviation. Kinetic profiles during cultivation time of: glucose concentration, bacterial biomass and NAI-107 production yields (panel a); inorganic (Pi) and organic (Po) phosphate concentration (panel b); pH values and ammonia concentration (panel c). Squares: glucose Triangles: percentage of packed mycelium volume (PMV %). Asterisks: NAI-107. Black circles: Pi. Empty circles: Po. Black diamonds: pH. Empty diamonds: ammonia. In A panel, numbered arrows represent time points of biomass sampling: 1, A-66 h; 2, A-90 h; 3, D-117 h; 4, D-140 h; 5, D-162 h