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Table 1 Predicted open reading frames (ORFs) identified in different structural regions of the Macropodid herpesvirus 1 genome and percentage pairwise amino acid identity to ORFs in related alphaherpesviruses

From: The first genome sequence of a metatherian herpesvirus: Macropodid herpesvirus 1

     % aa pairwise identity#
ORF Length (nt) Length (aa) Description (putative) § MaHV2 MaHV4 HHV1 HHV2
Unique short region
 US1 1392 463 Infected cell protein 22; ICP22    29 35
 US2 867 288 Tegument protein    49 49
 US3 1449 482 Protein kinase    56 59
 US4 360 119 Glycoprotein G; predicted non-functional 59 63 32 35
 US6 1188 395 Glycoprotein D 74   56 57
 US7 1392 463 Glycoprotein I 58   38 39
 US8 1599 532 Glycoprotein E 63   34 32
 PW2 342 113 Unique hypothetical     
 PW3 582 193 Unique hypothetical     
 PW4 1023 340 Unique hypothetical     
 PW5 1233 410 Unique hypothetical     
Inverted repeat region      
 PW1 453 150 Unique hypothetical     
 ICP4 3708 1235 Infected cell protein 4; ICP4    51 50
 TS 951 316 Thymidylate synthase; host-derived     
 ICP34.5 900 299 Infected cell protein 34.5; ICP34.5    62 56
 ICP0 1629 542 Infected cell protein 0; ICP0    50 51
Unique long region
 UL1 579 192 Glycoprotein L    41 47
 UL2 906 301 Uracil-DNA glycosylase    59 60
 UL5 2601 866 Helicase-primase helicase subunit    73 73
 UL6 2007 668 Capsid portal protein    62 63
 UL7 888 295 Tegument protein    51 49
 UL8 2253 750 Helicase-primase subunit    38 39
 UL9 2616 871 DNA replication origin-binding helicase    70 70
 UL10 1347 448 Glycoprotein M    51 48
 UL11 246 81 Myristoylated tegument protein    45 59
 UL12 1749 582 Alkaline exonuclease; deoxyribonuclease    56 56
 UL13 1845 614 Tegument serine/threonine protein kinase    48 47
 UL14 645 214 Tegument protein    60 63
 UL15 2100 699 DNA packaging terminase subunit 1    70 71
 UL16 1098 365 Tegument protein    51 54
 UL17 2184 727 DNA packaging tegument protein    51 50
 UL18 951 316 Capsid triplex subunit 2    68 68
 UL19 4131 1376 Major capsid protein    69 70
 UL20 648 215 Envelope protein    45 43
 UL21 1596 531 Tegument protein    43 43
 UL22 2631 876 Glycoprotein H    45 45
 UL23 1062 353 Thymidine kinase 76   42 44
 UL24 702 233 Nuclear protein    52 53
 UL25 1740 579 DNA packaging tegument protein    61 61
 UL26 1761 586 Capsid maturation protease    53 52
 UL27 2664 887 Glycoprotein B 83 82 72 70
 UL28 2325 774 DNA packaging terminase subunit 2    64 63
 UL29 3579 1192 ICP8; single stranded binding protein    70 69
 UL30 3675 1224 DNA polymerase    66 66
 UL31 921 306 Nuclear egress lamina protein    73 72
 UL32 1731 576 DNA packaging protein    62 61
 UL33 390 129 DNA packaging protein    61 60
 UL34 837 278 Nuclear egress membrane protein    44 43
 UL35 408 135 Small capsid protein    53 50
 UL36 8535 2844 Large tegument protein    48 48
 UL37 3150 1049 Tegument protein    46 45
 UL38 1359 452 VP19C; capsid triplex subunit 1    56 56
 UL39 2916 971 Ribonucleotide reductase subunit 1    65 66
 UL40 990 329 Ribonucleotide reductase subunit 2    65 65
 UL41 1566 521 Tegument host shutoff protein    60 61
 UL42 1422 473 DNA polymerase processivity subunit    44 44
 UL44 1296 431 Glycoprotein C    36 34
 UL45 516 171 Membrane protein    42 40
 UL46 2343 780 VP11/12; tegument protein    49 49
 UL47 2133 710 VP13/14; tegument protein    43 42
 UL48 1497 498 VP16; transactivating tegument protein    47 47
 UL49 777 258 VP22; tegument protein    67 67
 UL49A 324 107 Glycoprotein N     32
 UL50 1035 344 Deoxyuridine triphosphatase    39 35
 UL51 741 246 Tegument protein    67 66
 UL52 3102 1033 Helicase primase subunit    59 58
 UL53 1023 340 Glycoprotein K    46 47
 UL54 1524 507 ICP27; multifunctional expression regulator    52 52
 UL55 540 179 Nuclear protein    40 36
 PW6 630 209 Unique hypothetical     
  1. §Putative function of encoded polypeptides in MaHV-1
  2. #amino acid identities with homologues in Human herpesvirus 1 and 2 (HHV1 and HHV2) and Macropodid herpesviruses 2 and 4 (MaHV2 and MaHV4)