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Table 1 Candidate temperature-responsive genes

From: RNA-seq analysis of the gonadal transcriptome during Alligator mississippiensis temperature-dependent sex determination and differentiation

Day 0 – Day 3 MPT: MPT dimorphic (up-regulated)
Description RefSeq Accession No. Log2(FC) FDR Primary ontology
 Uncoupling protein 2 (mitochondrial, proton carrier) XM_006257947.1 1.47 2.63E-03 P: liver regeneration
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 XM_006262802.1 1.46 2.63E-03 C: Golgi membrane
 Eukaryotic translation initiation factor 4A2 XM_006262029.1 1.18 2.63E-03 F: translation initiation factor activity
 Uroplakin 3A XM_006265339.1 1.09 2.63E-03 C: integral to membrane
 Low-density lipoprotein receptor-related protein 1-like XM_006265415.1 1.09 2.63E-03 P: lipoprotein transport
 Acyl-coenzyme A synthetase ACSM4, mitochondrial-like XM_006273705.1 1.01 2.63E-03 F: catalytic activity
 Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 XM_006264916.1 0.97 2.63E-03 P: proline transmembrane transport
 Transient receptor potential cation channel, subfamily C, member 4 associated protein XM_006258376.1 0.91 2.63E-03 C: Cul4A-RING ubiquitin ligase complex
 CCAAT/enhancer binding protein (C/EBP), alpha XM_006274301.1 0.90 2.63E-03 P: regulation of cell proliferation
 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial-like XM_006273834.1 0.86 2.63E-03 F: ligase activity
 Myosin XVIIIB XM_006261765.1 0.86 2.63E-03 C: nucleolus
 Chromosome unknown open reading frame, human C1orf63 XM_006276772.1 0.80 2.63E-03 N/A
 Interferon-related developmental regulator 1, transcript variant X2 XM_006278568.1 0.69 2.63E-03 P: myoblast fate determination
 Espin-like XM_006276123.1 0.65 2.63E-03 N/A
 Prenylcysteine oxidase 1 XM_006268735.1 0.62 9.85E-03 C: lysosome
 Formimidoyltransferase cyclodeaminase XM_006260991.1 0.57 6.57E-03 C: cytosol
 Uncharacterized LOC102563416 XR_363102.1 infinite 4.73E-03 C: cytosol
Day 0 – Day 3 MPT: FPT dimorphic (down-regulated)
Description RefSeq Accession No. Log2(FC) FDR Primary Ontology
 Lysine (K)-specific demethylase 6B XM_006271864.1 -1.42 2.63E-03 P: positive regulation of transcription from RNA polymerase II promoter
 Protein Jumonji-like XM_006270621.1 -1.32 2.63E-03 P: negative regulation of transcription from RNA polymerase II promoter
 Protein Jumonji-like XM_006270617.1 -1.32 2.63E-03 P: negative regulation of transcription from RNA polymerase II promoter
 Cysteine and glycine-rich protein 2 XM_006269901.1 -1.31 2.63E-03 P: multicellular organismal development
 Myeloid protein 1-like XM_006275897.1 -1.30 2.63E-03 P: granulocyte differentiation
 Protease, serine, 35 XM_006258407.1 -1.24 2.63E-03 C: extracellular region
 ADAM metallopeptidase with thrombospondin type 1 motif, 15 XM_006262089.1 -1.24 2.63E-03 F: metalloendopeptidase activity
 Cellular retinoic acid binding protein 2 XM_006275867.1 -1.18 2.63E-03 F: retinoic acid binding
 Angiopoietin-like 1, transcript variant X2 XM_006267260.1 -1.18 2.63E-03 C: extracellular space
 Transgelin XM_006278069.1 -1.14 2.63E-03 F: protein binding, bridging
 Dimethylaniline monooxygenase [N-oxide-forming] 3-like XM_006259136.1 -1.06 2.63E-03 C: endoplasmic reticulum membrane
 Elastin XM_006267934.1 -1.05 2.63E-03 N/A
 Uncharacterized LOC102575456, transcript variant X1 XR_363216.1 -1.03 2.63E-03 N/A
 Hematopoietic prostaglandin D synthase XM_006265263.1 -1.01 4.73E-03 C: cytoplasm
 Hemoglobin subunit epsilon-like XM_006259088.1 -0.95 2.63E-03 P: oxygen transport
 Matrix-remodelling associated 5 XM_006277556.1 -0.94 2.63E-03 C: extracellular region
 Epidermal retinol dehydrogenase 2-like XM_006277024.1 -0.90 8.24E-03 P: retinal metabolic process
 v-myb avian myeloblastosis viral oncogene homolog-like 2 XM_006276553.1 -0.82 2.63E-03 P: spindle assembly involved in mitosis
 Protein Wnt-11-like, transcript variant X2 XM_006265079.1 -0.76 4.73E-03 P: positive regulation of apoptotic process
 Thrombospondin 2, transcript variant X1 XM_006277394.1 -0.73 2.63E-03 C: basement membrane
 Protein NEL-like XM_006272242.1 -0.66 2.63E-03 F: kinase activity
 Platelet-derived growth factor D-like XM_006268644.1 -0.63 4.73E-03 P: regulation of peptidyl-tyrosine phosphorylation
 RAS-like, family 11, member B XM_006261252.1 -0.63 6.57E-03 P: small GTPase mediated signal transduction
 Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) XM_006258484.1 -0.58 4.73E-03 F:cysteine-type endopeptidase activity