Network ID | Molecules in network | Score | Focus molecules | Top diseases and functions |
---|---|---|---|---|
1 | ACER2, ACIN1, ACVR1C, ALDH1A2, ARHGEF7, BCL11B, caspase, CBFB, CD38, CD44, CLCN3, CUL5, DPYD, EEF1A2, FGL2, Fibrinogen, ITGB1, MAP3K1, MAP3K8, MAPK8, MAPK9, MIF, MTDH, PAK1, PRDX6, Rac, RAD23B, SPARC, Srebp, TNKS2, TTLL1, VCL, WNT5A, ZBTB18, ZYX | 50 | 31 | Cell Death and Survival, Cellular Movement, Ophthalmic Disease |
2 | ABCA1, AURKAIP1, BRINP1, BTG2, CACNA1G, CAV1, CCND1, CDK2, DCK, GCLC, Histone h3, Histone h4, Insulin, IRAK1, KMT2A, LCN2, MAFG, MTMR1, P110, PIAS1, PPARGC1B, Pro-inflammatory Cytokine, Ras homolog, RBM5, RNA polymerase II, SBF1, SETD8, SLC18A2, SMARCA2, SOX2, STAT1, TRPM7, ZBTB7A, ZMYND11, ZNF148 | 44 | 28 | Cell Death and Survival, Gene Expression, Cellular Growth and Proliferation |
3 | ADNP, AHI1, ANKS1B, ARL6IP1, CDK11A, CXCL12, DNAJB6, ENC1, estrogen receptor, FBXO9, FBXW7, FGFR3, G2E3, Hdac, HSP, Hsp90, HSP90AA1, HSP90AB1, HSPB1, KLF9, KLF13, LINGO1, MED1, MED14, mediator, PA2G4, PGR, PPP3CB, RNF4, STUB1, THRA, TRAP/Media, TUFM, Ubiquitin, VPS41 | 43 | 28 | Cell Death and Survival, Post-Translational Modification, Protein Folding |
4 | A2M, ACACA, AKT2, ALDH1A1, Alp, AMPK, ATG12, ATP1A1, BSG, CA3, EIF5B, ENTPD5, FGF9, FGFR1, Focal adhesion kinase, FOXO1, KRAS, MAP1B, MEF2A, Mlc, NLK, NTRK3, PALLD, PDPK1, PITX2, PPP3R1, PRKAA1, PRKCD, PSMA7, RASSF4, RPS24, Serbp1, Sfk, STK17B, TAOK1 | 41 | 30 | Cell Death and Survival, Carbohydrate Metabolism, Cellular Development |
5 | ACAC, AP2B1, APAF1, APC-AXIN-GSK3β, ATP2A2, ATP2B1, ATP2B2, BAX, Ca2 ATPase, calpain, CAST, CDH13, Cytochrome bc1, cytochrome C, cytochrome-c oxidase, DDIT4, DNM1L, GBX2, glutathione peroxidase, GSK3B, ITSN1, KCND2, LMO4, MAFB, MAOA, MFN1, Mitochondrial complex 1, MTF2, NCS1, NDUFAB1, NFE2L1, OPA1, PACS2, PEX11B, PRKAA2 | 39 | 26 | Cell Death and Survival, Cell Cycle, Cellular Compromise |
6 | Ap1, ARHGAP1, ARL6IP5, CCDC86, CCND2, CEBPD, Cg, COL1A1, DACH1, FSH, Growth hormone, Gsk3, IGFBP3, Lh, MGEA5, NEO1, PDHA1, PPP2R1A, PRLR, PSIP1, PURA, RAB27A, RPRM, RSF1, SMAD4, SMAD7, Smad1/5/8, Smad2/3, SP1, SPP1, TAF4B, Tgf beta, TIMP1, TNRC6A, ZMYM2 | 39 | 26 | Cell Death and Survival, Tissue Development, Cellular Growth and Proliferation |