Fig. 7

Tager 104 νSaβ Genomic Island Shows Intermediate Clinical Adaptation. Representatives from each subtype of the νSaβ locus were selected and compared using the RAST server. Current strains of community acquired MRSA (CA-MRSA) contain the bsa locus (red arrows), which encodes a bacterial antibiotic. In contrast, hospital-acquired MRSA (HA-MRSA) have lost the bsa locus and instead gained enterotoxins (yellow arrows), an adaptation which has been previously associated with a selection for hospital settings. Results indicate Tager 104 has lost the bsa locus, but lacks the enterotoxin cluster (yellow) that has also been associated with this shift. In contrast, ruminant-host MSSA shows a wide range of these genotypes