Table 3 Most significantly associated SNPs identified in the PLINK analysis
Chr: Position | rs ID number | Feature | Base change | MAF: Cases (Controls) | Gene (distance to nearest genes) | Uncorrected p-value (0PCs) | FDR corrected (0PCs) | Uncorrected (2PCs) | FDR corrected (2PCs) |
|---|---|---|---|---|---|---|---|---|---|
9: 5,980,030 | Novel | intronic | A to G | 0.048(0.065) | KIAA2026 | 5.323e–008 | 0.0002117 | 1.587e–007 | 0.0005407 |
10: 8,542,529 | Novel | Intergenic | T to G | 0.016(0.028) | LINC00708(232261), LINC00709(775047) | 3.576e–007 | 0.0009478 | 2.461e–007 | 0.000734 |
12: 50,554,103 | Novel | intronic | A to G | 0.026(0.033) | CERS5 | 2.926e–007 | 0.0008725 | 6.119e–007 | 0.001622 |
12: 51,243,510 | Novel | intronic | A to T | 0.049(0.057) | TMPRSS12 | 7.362e–008 | 0.0002509 | 1.104e–007 | 0.0004388 |
14: 54,603,486 | rs116055771 | Intergenic | A to T | 0.013(0.022) | BMP4(179,932), CDKN3(260,187) | 4.085e–011 | 3.248e–007 | 2.014e–010 | 1.602e–006 |
15: 33,008,360 | Novel | Intergenic | A to C | 0.034(0.054) | SCG5(19,062), GREM1(1,845) | 6.384e–009 | 3.046e–005 | 2.652e–008 | 0.0001265 |
15: 33,345,877 | Novel | intronic | A to C | 0.004(0.011) | FMN1 | 2.048e–011 | 2.443e–007 | 6.591e–011 | 7.861e–007 |
18: 46,119,756 | Novel | intronic | T to C | 0.010(0.021) | CTIF | 2.128e–009 | 1.736e–006 | 5.41e–010 | 3.226e–006 |
18: 46,119,757 | rs76590328 | intronic | C to T | 0.031(0.054) | CTIF | 6.103e–013 | 1.456e–008 | 1.98e–012 | 4.724e–008 |
18: 46,503,254 | Novel | intronic | A to G | 0.031(0.057) | LOXHD1 | 2.722e–006 | 0.006494 | 4.838e–006 | 0.01154 |