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Table 1 Average FPRs and TPRs under the suggested settings of (w, n c ) for the data without and with noise interference

From: An integrated analysis tool for analyzing hybridization intensities and genotypes using new-generation population-optimized human arrays

Level of noise interference Suggested settinga FPR and TPR (Simulation scenario) Number of SNPs in the target region
(w, n c ) N T  = 11 N T  = 51 N T  = 101 N T  = 501
Without noise interference (q% = 0 %) (11, 2) Average FPR (neutral) 1.12 % 1.12 % 1.12 % 1.12 %
  Average TPR (loss) 95.55 % 94.08 % 95.39 % 95.43 %
  Average TPR (gain) 99.39 % 96.69 % 95.59 % 95.83 %
With noise interference (q% = 25 %) (51, 3) Average FPR (neutral) 2.19 % 2.19 % 2.19 % 2.19 %
  Average TPR (loss) 42.09 % 85.45 % 94.03 % 93.54 %
  Average TPR (gain) 50.67 % 89.37 % 92.81 % 93.55 %
  1. a w Window size, n c Number of consecutive significant SNPs, FFRs False positive rates, TPRs True positive rates, N T Number of SNPs in the target region