Table 4 Selected transcripts with annotated functions (GO terms) related to immune response that were over-expressed during M. mercenaria systemic response against QPX. Additional information on these transcripts is given in Additional file 3. “Inf” designates an infinite fold change calculated for focal response as the expression of that transcript in non-nodule tissue was equal to 0
From: Clam focal and systemic immune responses to QPX infection revealed by RNA-seq technology
Transcripts ID | Annotation | Regul-ation | Fold change | Function/GOs |
|---|---|---|---|---|
Stress protein | ||||
comp39934_c1_seq1 | heat shock 70 kda protein | Up | Inf | P:response to stress |
comp181704_c3_seq49 | heat shock 70 kda protein 12b | Up | 452.9 | - |
comp68505_c0_seq1 | heat shock protein 70 | Up | 37.8 | P:response to stress |
comp38810_c0_seq1 | hsp90 family member | Up | 64.7 | P:response to stress |
comp192296_c2_seq3 | usp-like protein isoform 2 | Up | 46.2 | P:response to stress |
Immune effectors | ||||
comp192209_c0_seq3 | hemocyte defensin partial | Up | 173.5 | P:defense response |
comp186386_c5_seq2 | c-type lysozyme 2 | Up | 20.0 | - |
comp186386_c5_seq1 | c-type lysozyme 2 | Up | Inf | - |
comp164821_c0_seq2 | c1q domain containing protein | Up | 8.3 | Lectin |
comp164821_c0_seq3 | c1q domain containing protein | Up | 11.9 | Lectin |
comp190576_c0_seq27 | low affinity immunoglobulin epsilon fc receptor | Up | 134.1 | F:carbohydrate binding; Lectin |
comp190576_c0_seq26 | low affinity immunoglobulin epsilon fc receptor | Up | 201.6 | F:carbohydrate binding; Lectin |
comp191987_c0_seq10 | macrophage mannose receptor 1-like | Up | 7.8 | F:carbohydrate binding; Lectin |
comp189507_c1_seq9 | ferric-chelate reductase 1 | Up | 10.7 | Iron transport |
Peptidases | ||||
comp156268_c1_seq1 | cathepsin k-like | Up | 9.5 | - |
comp184090_c0_seq6 | calpain 11-like | Up | 10.1 | - |
comp189096_c0_seq4 | counting factor associated protein d-like | Up | 36.1 | F:cysteine-type peptidase activity |
comp176418_c0_seq1 | isoaspartyl peptidase | Up | 8.0 | F:hydrolase activity |
Anti-apoptotic factors | ||||
comp178822_c0_seq1 | interleukin IL17-like | Up | 11.6 | P:inflammatory response; F:cytokine activity |
comp176786_c2_seq3 | deoxyguanosine mitochondrial | Up | 29.5 | F:tumor necrosis factor receptor binding; P:immune response; |
comp192603_c1_seq8 | baculoviral iap repeat-containing protein 7-a | Up | 10.3 | P:negative regulation of peptidase activity |
comp192603_c1_seq7 | baculoviral iap repeat-containing protein 7-a | Up | 14.3 | P:negative regulation of peptidase activity |
comp191786_c0_seq3 | baculoviral iap repeat-containing protein partial | Up | 8.9 | - |