From: Smokescreen: a targeted genotyping array for addiction research
Category | Markersa |
---|---|
1014 addiction-related genes | |
Tag SNPs (MAF ≥ 0.05) | 255862 |
Exonic markers | 17632 |
Genome-wide association markers | |
Affymetrix’ Axiom® Biobank GWAS grid | 246038 |
African (YRI) booster panel | 50000 |
Fine-mapping of smoking related loci | |
CHRNA5-CHRNA3-CHRNB4 (552 kb LD block) | 8913 |
CYP2A6 (±20 kb) | 573 |
CYP2B6 (±20 kb) | 1613 |
High-value addiction markers | |
NeuroSNP Project | 4994 |
Pharmacogenetics of Nicotine Addiction Treatment (PNAT) SNP panels | 2271 |
v1.0 Quit Success Score | 12058 |
Literature search | 1329 |
Comorbidity markers | |
Lung Cancer | 3091 |
Psychiatric disorders | 1200 |
Tobacco smoke constituent update and metabolic phenotypes | 1907 |
Pulmonary diseases and traits | 7945 |
Cardiovascular diseases and traits | 2247 |
General high-value markers | |
Pharmacogenomic markers | 2030 |
NHGRI GWAS Catalog | 7612 |
eQTLs | 9736 |
Loss-of-function markers | 4680 |
Ancestry informative markers (AIMs) | 5545 |
HLA/KIR | 8894 |
Mitochondrial | 180 |
Array Total | 646247 |