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Fig. 5 | BMC Genomics

Fig. 5

From: Reconstruction of gene regulatory modules from RNA silencing of IFN-α modulators: experimental set-up and inference method

Fig. 5

Inference of putative regulatory modules. a A summary of genes significantly modulated by STAT1 and IFIH1 silencing, extracted from Fig. 4. Since IFIH1 was significantly down-regulated by STAT1 silencing, each gene reported in the table is the common target of a FFL motif involving STAT1 and IFIH1. b The inferred six-output FFL regulatory module. Lines represent influence regulations in the stimulation (2 h/8 h; solid line) and wash-out (12 h; dashed line) phase. Arrow styles stand for: arrow, activation; ⊣, repression; dot, unspecified sign of regulation

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BMC Genomics

ISSN: 1471-2164

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