Skip to main content

Table 3 Number of significant SNPs (P < 10−5) in reference population that were also significant in the validation population

From: Detailed phenotyping identifies genes with pleiotropic effects on body composition

P value in validation No. of SNP FDR% %-same
multi-trait    
0.0001 17 0.05 100
0.001 24 0.3 100
0.01 31 2.2 100
0.05 35 9.5 100
all 98   73
single-trait (PSWT)    
0.0001 2 0.2 100
0.001 4 0.9 100
0.01 4 9.2 80
0.05 5 34.2 83
all 29   71
single-trait (LEGBONE)    
0.0001 8 0.06 100
0.001 9 0.5 100
0.01 13 3.4 100
0.05 17 11.2 100
all 48   84
single-trait (DRESS%)    
0.0001 2 0.19 100
0.001 3 1.23 100
0.01 7 4.67 100
0.05 9 16.4 90
all 31   78
single-trait (CCFAT)    
0.0001    
0.001 1 2.2 100
0.01 3 6.6 100
0.05 4 22.6 100
all 19   83
  1. %-same = percentage of SNPs, which have an effect in the same direction in both validation and reference sets