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Table 4 Total number of significant SNPs (P < 5 × 10−7), their FDR (%), and number of significant SNP on each chromosome (which is in parenthesis) for the 23 linear indexes corresponding to the 23 lead SNPs

From: Detailed phenotyping identifies genes with pleiotropic effects on body composition

Groupa SNP order Linear indexb code Mappedc gene code Total No. SNPd FDR (%) chromosome number (number of significant SNPse)
1 1st OAR16_31.9 Mb GHR 86 0.30 3 (1), 6 (83), 8 (1), 24 (1)
1 2nd OAR14_34.8 Mb LCAT    
1 3rd OAR11_26.4 Mb SLC16A11 231 0.11 1 (2), 3 (1), 5 (2), 6 (218), 9 (4), 11 (2), 13 (2)
1 4 th OAR6_37.5 Mb LCORL 489 0.05 1 (3), 2 (1), 6 (475), 7 (1), 9 (2), 11 (6), 15 (1)
2 5th OAR26_13.99 Mb ACSL    
2 6th OAR11_13.3 Mb ACACA 8 3.19 11 (6), 17 (2)
2 7th OAR11_49.9 Mb FASN 12 2.13 5 (1), 11 (6), 13 (4), 24 (1)
2 8th OAR6_15.2 Mb SNORA70 14 1.82 6 (12), 11 (1), 13 (1)
3 9th OAR19_57.1 Mb MRPS25 3 8.50 1 (1), 3 (2)
3 10th OAR2_219.6 Mb PLCD4 57 0.45 1 (3), 2 (54)
3 11th OAR3_17.9 Mb APOL6 3 8.50 3 (2), 23 (1)
3 12th OAR5_93.4 Mb CAST 5 5.10 3 (1), 5 (1), 11 (1), 21 (2)
3 13th OAR18_64.5 Mb MEG8_2 32 0.80 18 (32)
4 14 th OAR8_25.0 Mb     
4 15th OAR22_20.3 Mb PKD2L1 11 2.32 1 (1), 6 (2), 18 (8)
4 16th OAR12_49.6 Mb SAMD11 15 1.70 12 (14), 17 (1)
5 17th OAR14_54.6 Mb GYS1 10 2.55 2 (6), 4 (1), 10 (1), 18 (2)
5 18th OAR3_21.9 Mb PNPLA3    
5 19th OAR21_39.7 Mb FADS2    
5 20th OAR19_30.8 Mb 5S-rRNA    
5 21st OAR20_44.1 Mb SMIM13 9 2.83 20 (9)
5 22nd OAR21_14.96 Mb     
5 23rd OAR15_47.5 Mb U1 1 25.51 25 (1)
  1. a = Group of the lead SNPs that were clustered together as shown on Fig. 5
  2. b = 23 linear indexes corresponding to the 23 lead SNPs
  3. c = Genes located within 30 kb from each of lead SNPs excluding LCORL, and gene names are in Table 6
  4. d = Total number of significant SNPs which are significantly (P < 5 × 10−7) associated with each of linear indexes
  5. e = Number of significant SNP on each chromosome is in parentheses