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Table 2 Biological Process GO terms significally enriched in the clusters of the gene co-expression network ChlamyNET and the Metabolic and Signalling Pathways contained in each cluster

From: ChlamyNET: a Chlamydomonas gene co-expression network reveals global properties of the transcriptome and the early setup of key co-expression patterns in the green lineage

Cluster

Functional Annotation

Representative Genes

Metabolic/Signalling Pathways

Cluster 2 (Brown) 535 genes Silhoutte 0.44

DNA replication (GO:0006260)

Cre01.g015250 - POLD1 Cre16.g651000 - RFA1

Pyrimidine deoxyribonucleotides de novo biosynthesis pathway Cre16.g667850 - DUT Cre17.g715900 - THY Cre03.g190800 - TMPK

Chromosome organization (GO:00051276)

Cre02.g086650 - SMC2 Cre12.g4 934 00 - SMC4

Regulation of Cell Cycle (GO:0010564)

Cre10.g466200 - CYCAB1 Cre03.g207900 - CYCA1

Cluster 9 (Blue) 1058 genes Silhouette 0.40

protein phosphorylation (GO:0006468)

Cre17.g742400 - PTK17 Cre12.g537400 - CrAUR3

Starch Biosynthetic Pathway Cre04.g215150 - SSS Sucrose Biosynthetic Pathway Cre06.g283400 - SPP Nitrogen Assimilation Pathway Cre09.g410750 - NII1

carbohydrate metabolic process (GO:0005975)

Cre08.g384750 - AMY Cre10.g444700 - SBE3

transmembrane transport (GO:0055085)

Cre09.g396000 - NRT2.3 Cre13.g564650 - MRS5

Cluster 1 (Orange) 824 genes Silhouette 0.38

vesicle-mediated transport (GO:0016192)

Cre17.g728150 - Yky6 Cre16.g676650 - AP1G1

TAG Biosynthetic Pathway Cre02.g106400 - PDAT Phospholipid Biosynthetic Pathway Cre01.g035500 - PI3K Coenzyme A Biosynthetic Pathway Cre01.g048050 - COAB

GTPase activity (GO:0043087)

Cre12.g532600 - CGL44 Cre07.g315350 - RABGAP

Autophagy (GO:0006914)

Cre09.g391500 - APG9

Cluster 3 (Red) 1723 genes Silhouette 0.28

protein phosphorylation (GO:0006468)

Cre02.g145500 - PTK24 Cre12.g498650 - ALK3

TAG Biosynthetic Pathway g9572 - DGAT1 Hydrogen production Cre09.g396600 - HYDA2 MAP kinase cascade Cre10.g461150 - CrMAPKKK

ribosome biogenesis (GO:0042254)

Cre12.g532550 - RPL13a Cre09.g400650 - RPS6

macromolecule biosynthesis (GO:0009059)

Cre03.g207250 - GLN4

Cluster 4 (Purple) 1174 genes Silhouette 0.26

translation (GO:0006412)

Cre03.g199900 - EIF4E Cre02.g117900 - RH

tRNA Charging Pathway g2951 - TrpS Amino Acid Biosynthesis Cre03.g161400 - WSN2 Pentose Phosphate Non-oxydative Cre12.g511900 - RPE1 TAG Biosynthetic Pathway Cre03.g205050 - DGAT2

RNA processing (GO:0006396)

Cre16.g653050 - SpoU Cre10.g421600 - ThrRS g4 679 - RNase P

lipid metabolism (GO:0006629)

Cre09.g397250 - FAD5 Cre06.g295250 - PAP

Cluster 7 (Green) 909 genes Silhouette 0.25

protein complex assembly (GO:0006461)

g9912 - CSN5 Cre16.g663500 - CrRPN10

Aerobic Respiration Pathway Cre15.g638500 - CYC1 COP9 Signalling g11578 - CSN6

response to misfolded protein (GO:0051788)

Cre06.g280850 - PSMB4 Cre12.g501200 - SKP1

Cluster 6 (Yellow) 1351 genes Silhouette 0.24

chromatin organization (GO:0006325)

g11636 - HDA Cre13.g590750 - HTB37

Chromatin Remodelling Cre13.g591200 - HTB38 Cre13.g562400 - ABI3

posttranscriptional regulation (GO:0010608)

g7250 - DCL

Cluster 5 (Dark Green) 567 genes Silhouette 0.21

response to heat (GO:0009408)

Cre14.g617400 - HSP22F Cre08.g372100 - HSP70A

Stress Response Cre02.g098800 - ERP29 g9861 - TOR

protein folding (GO:0006457)

g9881 - FKBP Cre01.g047700 - CYP40

Cluster 8 (Turquoise) 1030 genes Silhouette 0.10

photosynthesis (GO:0015979)

Cre09.g412100 - PSAF Cre10.g44 04 50 - PSB28

Calvin Cycle Cre12.g554800 - PRK1 TCA Cycle Cre02.g143250 - IDH2

hexose metabolic process (GO:0019318)

Cre17.g725550 - GLD1 Cre02.g093450 - FBA2