Fig. 6

miRNA-gene network in the steroid hormone biosynthesis pathway [48] and regulatory network in early sex differentiation of Nile tilapia. The genes in boxes are differentially expressed in the mRNA-Seq and were validated by previous transcriptomic analyses [72]. Blue box nodes represent upregulated genes in XY gonads, red box nodes represent upregulated genes in XX gonads, and black box nodes represent genes with no significant difference between XX and XY. miRNAs in the ellipses potentially regulated the corresponding gene expression. Blue ellipses represent downregulated miRNAs in XX gonads; red ellipses represent downregulated miRNAs in XY gonads