Fig. 3From: Perturbation of the two-component signal transduction system, BprRS, results in attenuated virulence and motility defects in Burkholderia pseudomallei A Venn diagram showing the number of B. pseudomallei genes with increased expression (up arrow) or with reduced expression (down arrow) in each of the bprR, bprS and bprRS double mutants. Genes were identified as differentially expressed if they showed >2-fold expression change (log2 > 1.0) compared to the wild-type strain with a False Discovery Rate (FDR) of <0.01. The total number of genes in each mutant showing increased expression (>2-fold) with a more relaxed FDR of <0.05 are shown in bracketsBack to article page