Fig. 10
From: High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)
A SNP near the promoter region of ugt-5 increases in frequency 44× after lab adaptation. A G > C transversion found at below 1 % frequency in the ancestral C. remanei population has a 44× increase in frequency after 23 generations of laboratory adaptation. This SNP maps to the promoter region of a gene predicted to be homologous to the C. elegans gene ugt-5, which codes for an enzyme responsible for the removal of drugs, toxins, and foreign substances. The top panel shows 500 sequencing reads from the ancestral (wild) population; the bottom panel shows 500 sequencing reads from the lab-adapted population. The non-reference SNP at position 127,723,967 of the caeRem3 genome is visible in orange