Fig. 4

Analysis of DETs in chick thymus after Salmonella LPS treatment. Newly hatched chicks were injected i.p. with saline or 50 mg/kg Salmonella LPS and then sacrificed at defined time points (n = 7 ~ 9) to perform transcriptome analysis of the thymus. DETs were determined using the MARS model in DEGseq package between different time points (12 hpt vs. 0 hpt, 36 hpt vs. 0 hpt, 72 hpt vs. 0 hpt) with the same cut-off (P < 0.001, absolute fold change ≥ 1.5). a Numbers of DETs at different time point. b Top ten up- and down-expressed genes at different time point. The positive values indicate up-expression and negative values indicate down-expression