Fig. 3
MHC class I and SNP haplotype tracking in a F2 full-sib family. Detection of paternally and maternally inherited MHC class I haplotypes. Identification of three groups with the same MHC class I genotypes. Comparison and confirmation of MHC class I haplotypes with available genotype data (SNP-data) for each individual. rs-number: reference SNP cluster ID; Chr.P1/Chr.P2: alternative paternal haplotypes; Chr.M1/Chr.M2: alternative maternal haplotypes; orange box: cow which had calves with clinical BNP; blue boxes: cow which had calves showing no clinical BNP, but hematological deviations; green boxes: SNP alleles; yellow boxes: classical MHC class I alleles; grey boxes: non-classical MHC class I alleles; bluish strands: paternal chromatids; reddish strands: maternal chromatids. According to the Immuno Polymorphism Database (IPD-MHC; www.ebi.ac.uk/ipd/mhc/bola) haplotype 2*1601–6*1402 corresponds to haplotype A19, haplotype 1*03101–2*03201N corresponds to haplotype A13, haplotype 3*00402–3*01001_FBN8 is a variant of haplotype A2/A30