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Fig. 8 | BMC Genomics

Fig. 8

From: Selective forces and mutational biases drive stop codon usage in the human genome: a comparison with sense codon usage

Fig. 8

The minimum folding energy of mRNA regions surrounding the stop site. Minimum folding energy (MFE) of region I (RI), II (RII), and III (RIII) in mRNAs containing UAA, UAG, UGA, and in highly transcribed (HTG), housekeeping (HKG), and ribosomal protein (RPG) genes. Sequences are 50 nucleotides long. RI contains the coding sequence flanking the 5’ end of the stop codon (stop codon not included), RII is centred on the stop codon, and RIII is the 3’-UTR sequence flanking the stop codon (stop codon not included). Panels A and B report the average MFE of native and shuffled sequences, respectively. Values represent mean ± SEM

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BMC Genomics

ISSN: 1471-2164

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