Table 1 Relevance of prediction features ranked according to the information gain with respect to the class
From: KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily
Rank | Gain | Feature | Rank | Gain | Feature |
|---|---|---|---|---|---|
1 | 0.4914 | Gene Ontology | 14 | 4.79e-3 | Binding (UniProt) |
2 | 0.1787 | SIFT | 15 | 4.43e-3 | Np_bind (UniProt) |
3 | 0.1197 | Kinase group | 16 | 3.38e-3 | Repeat (UniProt) |
4 | 0.1121 | PFAM domain | 17 | 2.47e-3 | Phospho.ELM |
5 | 0.0438 | Wild type amino ac. | 18 | 2.37e-3 | Zn finger (UniProt) |
6 | 0.0373 | Hydrophobicity | 19 | 1.82e-3 | Modified res. (UniProt) |
7 | 0.0368 | Alternative amino ac. | 20 | 1.51e-3 | Metal binding (UniProt) |
8 | 0.0353 | Volume change | 21 | 9.4e-4 | Signal peptide (UniProt) |
9 | 0.0239 | FireDB residue | 22 | 7.71e-4 | Active site (UniProt) |
10 | 8.94e-3 | Any uniprot | 23 | 6.86e-4 | Carbohyd (UniProt) |
11 | 7.70e-3 | Formal charge | 24 | 5.02e-4 | Site (UniProt) |
12 | 6.80e-3 | Cbeta Branching | 25 | 5.33e-5 | Transmembrane (UniProt) |
13 | 6.02e-3 | Disulfid (UniProt) |