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Table 1 Harmful effects of two haplotypes with reduced homozygosity in Braunvieh (BH2) and Fleckvieh (BH2FV) cattle

From: A missense mutation in TUBD1 is associated with high juvenile mortality in Braunvieh and Fleckvieh cattle

Haplotype Chr Position Haplotype frequency (%) Number of calvings Difference in survival rate
Start (bp) Stop (bp) risk non-risk day 2 day 10 day 365 P
BH2 19 10,694,269 11,833,182 6.5 6,299 25,801 −2.1 −3.9 −4.6 1.8x10−28
BH2FV 19 10,406,017 11,453,904 1.7 1,296 45,270 −4.0 −4.0 −6.1 2.2x10−15
  1. The juvenile mortality of calves from risk matings was compared to non-risk matings. Matings between carrier bulls and cows descending from carrier bulls were considered as risk matings and matings between non-carrier bulls and cows descending from carrier bulls were considered as non-risk matings. The difference in survival rate refers to the proportion of additional calf losses in risk compared to non-risk matings. The physical position of the haplotypes was based on the UMD3.1 assembly of the bovine genome