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Table 2 Detailed information for the most widely present homologous gene clusters

From: Comparative genomics reveals multiple pathways to mutualism for tick-borne pathogens

Cluster # Representative protein accession # # of organisms in cluster Product description KEGG EC #
30 AAV86731 38 2,3-bisphosphoglycerate-independent phosphoglycerol mutase 5.4.2.12
30 AAV87091 38 nicotinate-nucleotide pyrophosphorylase 2.4.2.19
30 AAV87100 38 quinolinate synthetase A 2.5.1.72
29 NP_212375 35 glycerol kinase 2.7.1.30
28 AAV86691 33 1-deoxy-D-xylulose-5-phosphate reductoisomerase 1.1.1.267
28 AAV87137 33 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4.6.1.12
27 AHX03201 32 tRNA threonylcarbamoyladenosine biosynthesis protein TsaE no EC number
26 NP_212377 30 glycerol-3-phosphate dehydrogenase 1.1.5.3
25 AAV87130 25 hypothetical no entry
25 NP_359873 25 hypothetical no entry
25 AAV86484 25 pyridoxine 5-phosphate synthase 2.6.99.2
25 AAV86592 25 bifunctional proline dehydrogenase, pyrroline-5-carboxylate dehydrogenase 1.5.5.2, 1.2.1.88
25 AAV86778 25 thiamine biosynthesis oxidoreductase 1.4.3.19
24 NP_359861 24 divalent cation tolerance protein no entry
24 NP_360910 24 hypothetical no entry
24 NP_360096 24 hypothetical no entry
23 NP_360134 23 hypothetical no entry
23 NP_360791 23 hypothetical no entry
22 YP_001499275 22 AbrB family transcriptional regulator no entry
22 NP_360166 22 cell filamentation protein Fica no entry
22 NP_360392 22 hypothetical no entry
22 NP_360955 22 plasmid stability protein no entry
21 NP_359844 21 hypothetical no entry
21 NP_360418 21 biotin-protein ligase no entry
21 NP_360956 21 hypothetical no entry
  1. aThis gene was reported as one of three representative ORGs, RiOG_1005, i.e., present in all tick-borne Rickettsial genomes in the study by Gillespie et al. [27]