Fig. 3

Differentially expression analysis. a Number of differentially expressed genes. b Scatterplot of log2 fold changes in Rett syndrome samples relative to controls, as detected by RNA-seq (X-axis) and microarrays (Y-axis). All genes identified as differentially expressed genes are displayed, with each gene represented by a dot. Grey dots- genes not detected by microarrays, blue dots- genes that did not reach statistical significance for differential expression based on the microarray data, red dots- genes detected as differentially expressed by both RNA-seq and microarrays