Prediction of peptidoglycan hydrolases- a new class of antibacterial proteins

BMC Genomics

Table 4 Performance of HyPe on independent genomic dataset

Genome	Sensitivity	MCC
Alcanivorax pacificus RT type strain W11 5	71.43	0.56
Bacillus anthracis strain PAK 1	77.42	0.81
Bacillus cereus strain 03BB87	75.86	0.77
Bacillus subtilis T30	62.96	0.67
Bacillus thuringiensis strainHD571	84.00	0.86
Campylobacter jejuni subsp jejuni strain YH001	42.86	0.51
Chlamydia trachomatis strainL2b CS19 08	50.00	0.71
Clostridium botulinum strain NCTC8550	68.18	0.75
Cronobacter sakazakii SP291	85.71	0.74
Francisella tularensis subsp. novicida U112	100.00	0.82
Haemophilus influenzae strain Hi375	82.35	0.88
Halomonas sp strain KO116	88.89	0.94
Lactobacillus sp. wkB8	66.67	0.63
Listeria monocytogenes Serovar 4b Strain IZSAM Lm hs2008	92.31	0.86
Listeria monocytogenes strain NTSN	80.00	0.77
Mycobacterium tuberculosis H37RvSiena	100.00	0.78
Neisseria meningitidis LNP21362	78.57	0.65
Pasteurella multocida OH1905	62.50	0.59
Rickettsia rickettsii str Morgan	75.00	0.75
Staphylococcus aureus strain FCFHV36	77.27	0.81
Streptococcus iniae strain ISNO	60.00	0.63
Vibrio alginolyticus NBRC 15630	64.71	0.74
Vibrio tubiashii ATCC 19109	70.59	0.75
Weissella ceti strain WS74	60.00	0.67

The Specificity and Accuracy was almost 1 for all the above genomes since the number of True Negatives (TN) was very large in number, which used in the denominator for the calculation to Specificity and Accuracy

ISSN: 1471-2164