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Table 1 Summary of the results of the enrichment analysis using iHS scores as the baseline

From: Changes in selective pressures associated with human population expansion may explain metabolic and immune related pathways enriched for signatures of positive selection

Population

GSEA:

Daub et al. [19]

(# of gene sets)

GSEA:

GOWINDA

(# of gene sets)

Total # of pathways for each population, and the in common pathways between the two GSEA approaches

CEU

3

2

5 of which 1 in common

(Cell Cycle, Mitotic)

YRI

7

140

147 of which 3 in common

(DNA Repair, Spliceosome, Cell Cycle, Mitotic)

CHB + JTP

1

0

1

Total # of pathways for each GSEA approach, and the in common pathways among populations

11 of which 2 in common (Cell Cycle, Mitotic, Olfactory Signaling Pathway)

142 of which 2 in common (Dna Repair, Cell Cycle, Mitotic)

152 of which 5 in common

(Cell Cycle Mitotic, DNA Repair,

Spliceosome, Olfactory Signaling Pathway, G2/M checkpoints)