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Table 2 Summary of the results of the enrichment analysis using XPCLR scores as the baseline

From: Changes in selective pressures associated with human population expansion may explain metabolic and immune related pathways enriched for signatures of positive selection

Population pair

(Objective-Reference)

GSEA:

Daub et al. [19]

(# of gene sets)

GSEA:

GOWINDA

(# of gene sets)

Total # of pathways for each population, and the in common pathways between the two GSEA approaches

CEU-YRI

3

0

3

YRI- CEU

0

2

2

YRI- CHB + JTP

1

7

8 of which 1 in common

(Cell surface interactions at the vascular wall)

CHB + JTP-YRI

1

1

2

CEU- CHB + JTP

0

1

1

CHB + JTP-CEU

1

1

2

Total # of pathways for each GSEA

6

12

18 of which 1 in common

(Cell surface interactions at the vascular wall)

  1. The population on the left is considered to be the objective one, while the one on the right the reference one under all circumstances. Threshold is set to <0.09