Table 1 Characteristics of patients with invasive disease due to nontypeable and encapsulated Streptococcus pneumoniae, South Africa, 2003–2013
Characteristic | Nontypeable S. pneumoniae | Encapsulated S. pneumoniae | Total | |
|---|---|---|---|---|
N = 39 | N = 32785 | N = 32824 | ||
n (%) | n (%) | n (%) | ||
Year | 2003 | 2 (5) | 2885 (9) | 2887 (9) |
2004 | 4 (10) | 3465 (11) | 3469 (11) | |
2005 | 5 (13) | 3643 (11) | 3648 (11) | |
2006 | 5 (13) | 3411 (10) | 3416 (10) | |
2007 | 2 (5) | 3318 (10) | 3320 (10) | |
2008 | 6 (15) | 3319 (10) | 3325 (10) | |
2009 | 7 (18) | 3377 (10) | 3384 (10) | |
2010 | 3 (8) | 2869 (9) | 2872 (9) | |
2011 | 0 | 2409 (7) | 2409 (7) | |
2012 | 3 (8) | 2158 (7) | 2161 (7) | |
2013 | 2 (5) | 1931 (6) | 1933 (6) | |
Gender | Male | 23 (59) | 15842 (48) | 15865 (48) |
Female | 16 (41) | 16291 (50) | 16307 (50) | |
Unknown | 0 | 652 (2) | 652 (2) | |
Age group (years) | <5 | 17 (44) | 9446 (29) | 9463 (29) |
5–14 | 3 (8) | 2960 (9) | 2963 (9) | |
15–24 | 2 (5) | 1918 (6) | 1920 (6) | |
25–44 | 10 (26) | 11714 (36) | 11724 (36) | |
45–64 | 4 (10) | 4355 (13) | 4359 (13) | |
>64 | 2 (5) | 1137 (3) | 1139 (3) | |
Unknown | 1 (3) | 1255 (4) | 1256 (4) | |
Specimen type | Cerebrospinal fluid | 11 (28) | 11486 (35) | 11497 (35) |
Blood | 22 (56) | 19284 (59) | 19306 (59) | |
Othera | 6 (16) | 2015 (6) | 2021 (6) | |
PCV vaccinationb | Yesc | 2 (100) | 580 (77) | 582 (77) |
No | 0 | 131 (17) | 131 (17) | |
Unknown | 0 | 46 (6) | 46 (6) | |
PCV13 serotypesd | PCV13 serotypes | 13e (59) | 23619 (72) | 23632 (72) |
Non PCV13 serotypes | 9e (41) | 9166 (28) | 9175 (28) | |
HIV status | Positive | 5 (13) | 7718 (23) | 7723 (23) |
Negative | 5 (13) | 2489 (8) | 2494 (8) | |
Unknown | 29 (74) | 22578 (69) | 22607 (69) | |
Immuno compromising conditionsf | Yes | 2 (5) | 3114 (10) | 3116 (10) |
No | 13 (33) | 6974 (21) | 6987 (21) | |
Unknown | 24 (62) | 22697 (69) | 22721 (69) | |
Comorbid conditionsg | Yes | 2 (5) | 1496 (5) | 1498 (5) |
No | 13 (33) | 8592 (26) | 8605 (26) | |
Unknown | 24 (62) | 22697 (69) | 22721 (69) | |
Outcome | Died | 4 (10) | 4024 (12) | 4028 (12) |
Recovered | 14 (36) | 9887 (30) | 9901 (30) | |
Unknown | 21 (54) | 18874 (58) | 18895 (58) |