Fig. 1From: BASE: a practical de novo assembler for large genomes using long NGS readsOverview of the whole assembly method. There are five steps for one direction extension. Firstly, we choose an initial read by order and find an initial seed in this read. Then we use bi-directional BWT to get the SA ranges of this seed using backward exact matching. Thirdly, we build up a backward extension tree by adding bases to continue the backward matching. After removing erroneous branches and heterozygosis branches, we obtain the consensus sequence of the extended region. Finally, we continue to find a new seed in the extended region and extend iterativelyBack to article page