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Fig. 1 | BMC Genomics

Fig. 1

From: Genomic and expression analyses of Tursiops truncatus T cell receptor gamma (TRG) and alpha/delta (TRA/TRD) loci reveal a similar basic public γδ repertoire in dolphin and human

Fig. 1

Schematic representation of the genomic organization of the dolphin TRG locus as deduced from the genome assembly Ttru_1.4. a The diagram shows the position of all V, J and C genes according to the IMGT® nomenclature. The AMPH (located 15.5 kb upstream of the first TRGV gene) and the STARD3NL (located 11.6 kb downstream of the unique TRGC gene, in the inverted transcriptional orientation) genes at the 5′ end and at the 3′ end, respectively of the TRG locus are shown. Boxes representing genes are not to scale. Exons are not shown. b Description of the TRGV, TRGJ, and TRGC genes in the dolphin genome. The position of all genes in the JH473572.1 scaffold and their classification are reported. The bottlenose dolphin (Tursiops truncatus) TRG genes and alleles have been approved by the WHO/IUIS/IMGT nomenclature subcommittee for IG, TR and MH [66, 67]. a From L-PART1 to 3′ end of V-REGION. c IMGT Protein display of the dolphin, human and sheep TRGC genes. The description of the strands and loops is according to the IMGT unique numbering for C-DOMAIN [68]. The extracellular region is shown with black letters, the connecting region is in orange, the transmembrane-region is in purple, and the cytoplasmic region is in pink. 1st-CYS C23, CONSERVED-TRP W41 and hydrophobic AA L89 and 2nd-CYS C104 are colored (IMGT color menu) and in bold

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BMC Genomics

ISSN: 1471-2164

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