Skip to main content
Fig. 4 | BMC Genomics

Fig. 4

From: Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling

Fig. 4

Relative increased susceptibility to Chs1p inhibition of phr1Δ and phr1Δ chs2Δ chs8Δ mutants. The mutants CAS8 (phr1Δ) and FP138 (phr1Δ chs2Δ chs8Δ) and their parental strains CAI4 (wild type) and NGY138 (chs2Δ chs8Δ) were analyzed for sensitivity to RO-09-3143 by microdilution assay in M199-pH 7.5 37 °C, at an inoculum size of 5 x 105/ml. Data refer to 24 h. The results derive from 3 biological replicates and 2 microtiter plates for each replicate. Data are relative to untreated wild type which was set to 100 % (mean A595 = 0.600 ± 0.063 S.D.). The MB staining of cells from a representative experiment is shown in Additional file 5

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us