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Table 8 (abstract P22) Distribution of Genotypes and Alleles for IL1RN intron 2 VNTR (rs1794068) in vitiligo patients and controls from Gujarat. ‘n’ represents number of Patients/Controls

From: Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

SNP

Genotype or allele

Vitiligo Patients (Freq.)

Controls (Freq.)

p for Association

Odds ratio

CI (95%)

IL1RN intron 2 VNTR (rs1794068)

Genotype

n = 226

n = 226

   

(A 1/1)

85 (37.61)

93 (41.15)

R

1a

-

(A 1/2)

89 (39.38)

84 (37.16)

0.4891a

0.8626a

0.5674 to 1.311a

(A 2/2)

40 (17.69)

33 (14.6)

0.3109a

0.7540a

0.4364 to 1.303a

(A 3/2)

3 (1.32)

4 (1.76)

0.7992a

1.219a

0.2650 to 5.605a

(A 3/1)

8 (3.53)

9 (3.98)

0.9564a

1.028a

0.3794 to 2.787a

(A 4/2)

1 (0.44)

00 (0.00)

0.2970a

0.3048a

0.01224 to 7.589a

(A 1/4)

00 (0.00)

1 (0.44)

0.3403a

2.743a

0.1102 to 68.30a

(A 5/2)

00 (0.00)

2 (0.88)

0.1786a

4.572a

0.2163 to 96.66a

 

Allele

     
 

182(55.6)

    

A1

133(40.6)

187(57.3)

Rb

1b

-

 

11(3.36)

    

A2

 

123(37.7)

0.5177b

0.9001b

0.6542 to 1.238b

 

1(0.30)

    

A3

 

13(3.98)

0.7404b

1.150b

0.5022 to 2.634b

 

0(0)

    

A4

 

1(0.30)

0.9848b

0.9733b

0.06038 to 15.69b

A5

 

2(0.61)

0.1641b

4.867b

0.2319 to 102.1b

  1. ‘R’ represents reference group
  2. HWE refers to Hardy-Weinberg Equilibrium
  3. CI refers to Confidence Interval
  4. (P) refers to Patients and (C) refers to Controls
  5. aVitiligo Patients vs. Controls (genotype) using chi-squared test with 2 × 2 contingency table
  6. bVitiligo Patients vs. Controls (allele) using chi-squared test with 2 × 2 contingency table
  7. A are different alleles of IL1RN intron 2 VNTR (rs1794068)