Fig. 5

Biological process enrichment as a function of cultivation in methanol. Heat map representation of the enrichment of GO biological process terms for expression phenotypes observed in K. pastoris and K. phaffii during a 48 h batch cultivation in methanol as characterized by self-organizing maps (SOMs). Representative temporal trajectories of gene expression were generated for each SOM by averaging expression data at each time point for genes present within a given map. Color density relates to the number of genes assigned to a particular process as a percentage of the total number genes present in a particular expression phenotype or map