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Fig. 6 | BMC Genomics

Fig. 6

From: The Rat microRNA body atlas; Evaluation of the microRNA content of rat organs through deep sequencing and characterization of pancreas enriched miRNAs as biomarkers of pancreatic toxicity in the rat and dog

Fig. 6

Histopathologic assessment of the pancreases of rats treated with 15 and 50ug/kg of caerulein. Histopathologic assessment of organs was performed at 8, 24 and 48 h with dose, time and animal number indicated on the x-axis and the grade of injury indicated on the y-axis (grey-blue indicates slight injury, green indicates moderate injury, blue indicates minimal injury and pink indicates marked injury). Rat pancreases displayed minimal and slight pancreatic necrosis in 4 vehicle treated rats at 24 and 48 h while dose responsive increases in the severity of necrosis was noted in the 15 and 50ug/kg treatred rats at 8, 24 and 48 h

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